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NBAS Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | A2RRP1 |
|---|
| Gene ID | 51594 |
|---|---|
| Other Names | Neuroblastoma-amplified sequence, Neuroblastoma-amplified gene protein, NBAS, NAG |
| Target/Specificity | The synthetic peptide sequence is selected from aa 648-661 of HUMAN NBAS |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NBAS (HGNC:15625) |
|---|---|
| Function | Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:19369418). Required for normal embryonic development (By similarity). May play a role in the nonsense-mediated decay pathway of mRNAs containing premature stop codons (By similarity). |
| Cellular Location | Cytoplasm. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein |
| Tissue Location | Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Scott D.K.,et al.Gene 307:1-11(2003).
Hillier L.W.,et al.Nature 434:724-731(2005).
Wimmer K.,et al.Oncogene 18:233-238(1999).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Fruehwald M.C.,et al.J. Med. Genet. 37:501-509(2000).
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