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PDS5B Blocking Peptide (C-Term)

Synthetic peptide

     
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Product Information
Primary Accession Q9NTI5
Additional Information
Gene ID 23047
Other Names Sister chromatid cohesion protein PDS5 homolog B, Androgen-induced proliferation inhibitor, Androgen-induced prostate proliferative shutoff-associated protein AS3, PDS5B
Target/Specificity The synthetic peptide sequence is selected from aa 1217-1228 of HUMAN PDS5B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDS5B
Function Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q6TRW4}.
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Background

Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

References

Geck P.,et al.J. Steroid Biochem. Mol. Biol. 63:211-218(1997).
Geck P.,et al.J. Steroid Biochem. Mol. Biol. 68:41-50(1999).
Nagase T.,et al.DNA Res. 6:63-70(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 80.00
Cat# BP21942b
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