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INTS6 Blocking Peptide (N-Term)

Synthetic peptide

     
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  • CITATIONS
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  • BACKGROUND
Product Information
Primary Accession Q9UL03
Other Accession Q5JSJ4, Q8BND4, Q2TAF4, Q5U4W6, Q7SYD9, Q6PCM2
Additional Information
Gene ID 26512
Other Names Integrator complex subunit 6, Int6, DBI-1, Protein DDX26, Protein deleted in cancer 1, DICE1, INTS6, DBI1, DDX26, DDX26A
Target/Specificity The synthetic peptide sequence is selected from aa 155-167 of HUMAN INTS6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name INTS6
Synonyms DBI1, DDX26, DDX26A
Function Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.
Cellular Location Nucleus.
Tissue Location Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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Background

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.

References

Wieland I.,et al.Oncogene 18:4530-4537(1999).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Dunham A.,et al.Nature 428:522-528(2004).
Hoff H.B. III,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
Wieland I.,et al.Oncol. Res. 12:491-500(2001).

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$ 80.00
Cat# BP21956a
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