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AKR7A3 Blocking Peptide (N-Term)

Synthetic peptide

     
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Product Information
Primary Accession O95154
Other Accession Q8NHP1
Additional Information
Gene ID 22977
Other Names Aflatoxin B1 aldehyde reductase member 3, 1.-.-.-, AFB1 aldehyde reductase 2, AFB1-AR 2, AKR7A3, AFAR2
Target/Specificity The synthetic peptide sequence is selected from aa 33-44 of HUMAN AKR7A3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKR7A3
Synonyms AFAR2
Function Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Cellular Location Cytoplasm.
Tissue Location Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
Research Areas
Citations (0)

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Background

Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

References

Knight L.P.,et al.Carcinogenesis 20:1215-1223(1999).
Praml C.,et al.Oncogene 22:4765-4773(2003).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bodreddigari S.,et al.Chem. Res. Toxicol. 21:1134-1142(2008).

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$ 80.00
Cat# BP21993a
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