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THRSP Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q92748 |
|---|
| Gene ID | 7069 |
|---|---|
| Other Names | Thyroid hormone-inducible hepatic protein, Spot 14 protein, S14, SPOT14, THRSP |
| Target/Specificity | The synthetic peptide sequence is selected from aa 18-28 of HUMAN THRSP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | THRSP |
|---|---|
| Function | Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. |
| Cellular Location | Nucleus. Cytoplasm |
| Tissue Location | Mainly expressed in tissues that synthesize triglycerides |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
References
Grillasca J.-P.,et al.FEBS Lett. 401:38-42(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Chou W.Y.,et al.Biochem. Biophys. Res. Commun. 357:133-138(2007).
Chou W.Y.,et al.Int. J. Biochem. Cell Biol. 40:1826-1834(2008).
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