|Other Accession||P14099, Q922S4, Q01062|
|Other Names||cGMP-dependent 3', 5'-cyclic phosphodiesterase, 220.127.116.11, Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE, PDE2A|
|Target/Specificity||The synthetic peptide sequence is selected from aa 807-821 of HUMAN PDE2A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.|
|Cellular Location||Isoform PDE2A3: Cell membrane; Lipid-anchor Isoform PDE2A1: Cytoplasm|
|Tissue Location||Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Rosman G.J.,et al.Gene 191:89-95(1997).
Bugaj-Gaweda B.,et al.Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
Russwurm C.,et al.J. Biol. Chem. 284:25782-25790(2009).
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