MAN1A2 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O60476 |
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Gene ID | 10905 |
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Other Names | Mannosyl-oligosaccharide 1, 2-alpha-mannosidase IB, 3.2.1.113, Mannosidase alpha class 1A member 2, Processing alpha-1, 2-mannosidase IB, Alpha-1, 2-mannosidase IB, MAN1A2, MAN1B |
Target/Specificity | The synthetic peptide sequence is selected from aa 362-373 of HUMAN MAN1A2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MAN1A2 |
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Synonyms | MAN1B |
Function | Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). |
Cellular Location | Golgi apparatus membrane; Single-pass type II membrane protein |
Tissue Location | Highest levels of expression in placenta and testis |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
References
Tremblay L.O.,et al.Glycobiology 8:585-595(1998).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bienvenut W.V.,et al.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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