|Other Names||Mannosyl-oligosaccharide 1, 2-alpha-mannosidase IB, 220.127.116.11, Mannosidase alpha class 1A member 2, Processing alpha-1, 2-mannosidase IB, Alpha-1, 2-mannosidase IB, MAN1A2, MAN1B|
|Target/Specificity||The synthetic peptide sequence is selected from aa 362-373 of HUMAN MAN1A2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Highest levels of expression in placenta and testis|
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Provided below are standard protocols that you may find useful for product applications.
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
Tremblay L.O.,et al.Glycobiology 8:585-595(1998).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bienvenut W.V.,et al.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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