|Other Names||PML-RARA-regulated adapter molecule 1, PRAM, PRAM-1, PRAM1|
|Target/Specificity||The synthetic peptide sequence is selected from aa 607-618 of HUMAN PRAM1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P.|
|Tissue Location||Expressed in peripheral blood leukocytes and bone marrow. Expressed in monocytes, and to a lesser extent in granulocytes and lymphocytes. Not expressed in non hematopoietic tissues except in lung.|
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May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P.
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Heuer K.,et al.J. Mol. Biol. 361:94-104(2006).
Choudhary C.,et al.Science 325:834-840(2009).
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