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ANKRD1 Blocking Peptide (N-Term)

Synthetic peptide

     
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Product Information
Primary Accession Q15327
Other Accession Q3ZBX7, Q865U8
Additional Information
Gene ID 27063
Other Names Ankyrin repeat domain-containing protein 1, Cardiac ankyrin repeat protein, Cytokine-inducible gene C-193 protein, Cytokine-inducible nuclear protein, ANKRD1, C193, CARP, HA1A2
Target/Specificity The synthetic peptide sequence is selected from aa 22-34 of HUMAN ANKRD1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANKRD1
Synonyms C193, CARP, HA1A2
Function May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Cellular Location Nucleus
Tissue Location Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells
Research Areas
Citations (0)
citation

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Background

May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.

References

Chu W.,et al.J. Biol. Chem. 270:10236-10245(1995).
Park J.-H.,et al.Cancer Res. 65:2804-2814(2005).
Deloukas P.,et al.Nature 429:375-381(2004).
Miller M.K.,et al.J. Mol. Biol. 333:951-964(2003).
Cinquetti R.,et al.Hum. Mutat. 29:468-474(2008).

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$ 277.78
Cat# BP22032a
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