|Other Names||Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Microtubule plus-end tracking protein TIP150, Tracking protein of 150 kDa, MTUS2, CAZIP, KIAA0774, TIP150|
|Target/Specificity||The synthetic peptide sequence is selected from aa 937-949 of HUMAN MTUS2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CAZIP, KIAA0774, TIP150|
|Function||Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.|
|Cellular Location||Cytoplasm, cytoskeleton. Note=Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules|
|Tissue Location||Detected in embryonic stem cells differentiating to cardiomyocytes.|
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Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.
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Dunham A.,et al.Nature 428:522-528(2004).
Du Puy L.,et al.Dev. Dyn. 238:2903-2911(2009).
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