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ZNRD1 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9P1U0 |
|---|---|
| Other Accession | Q1RMP0, Q5TM50, Q791N7, Q1XHV8, Q6MFY5 |
| Gene ID | 30834 |
|---|---|
| Other Names | DNA-directed RNA polymerase I subunit RPA12, Zinc ribbon domain-containing protein 1, ZNRD1, RPA12 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 118-127 of HUMAN ZNRD1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | POLR1H (HGNC:13182) |
|---|---|
| Function | Core component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Can mediate Pol I proofreading of the nascent RNA transcript. Anchors into the Pol I active site to monitor transcription fidelity and cleave mis- incorporated 5'-ribonucleotides. |
| Cellular Location | Nucleus, nucleolus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
References
Fan W.,et al.Genomics 63:139-141(2000).
Shematorova E.K.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
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