RPS27 Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P42677 |
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Other Accession | Q2KHT7, Q6ZWU9, Q71TY3 |
Gene ID | 6232 |
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Other Names | 40S ribosomal protein S27, Metallopan-stimulin 1, MPS-1, RPS27, MPS1 |
Target/Specificity | The synthetic peptide sequence is selected from aa 5-17 of HUMAN RPS27 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RPS27 (HGNC:10416) |
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Synonyms | MPS1 |
Function | Component of the small ribosomal subunit (PubMed:8706699, PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Required for proper rRNA processing and maturation of 18S rRNAs (PubMed:25424902). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). |
Cellular Location | Cytoplasm. Nucleus, nucleolus |
Tissue Location | Expressed in a wide variety of actively proliferating cells and tumor tissues. |
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Provided below are standard protocols that you may find useful for product applications.
References
Fernandez-Pol J.A.,et al.J. Biol. Chem. 268:21198-21204(1993).
Tsui S.K.W.,et al.Biochem. Mol. Biol. Int. 40:611-616(1996).
Yoshihama M.,et al.Genome Res. 12:379-390(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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