HEXDC Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8WVB3 |
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Gene ID | 284004 |
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Other Names | Hexosaminidase D, 3.2.1.52, Beta-N-acetylhexosaminidase, Beta-hexosaminidase D, Hexosaminidase domain-containing protein, N-acetyl-beta-galactosaminidase, HEXDC |
Target/Specificity | The synthetic peptide sequence is selected from aa 155-166 of HUMAN HEXDC |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | HEXD (HGNC:26307) |
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Function | Has hexosaminidase activity. Responsible for the cleavage of the monosaccharides N-acetylglucosamine (GlcNAc) and N- acetylgalactosamine (GalNAc) from cellular substrates. Has a preference for galactosaminide over glucosaminide substrates (PubMed:27149221). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q3U4H6}. Nucleus {ECO:0000250|UniProtKB:Q3U4H6}. Extracellular vesicle |
Tissue Location | Expressed in synovial fibroblasts and synovial membranes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Has hexosaminidase activity.
References
Gutternigg M.,et al.Biochem. J. 419:83-90(2009).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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