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NAA40 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86UY6 |
|---|---|
| Other Accession | Q8VE10 |
| Gene ID | 79829 |
|---|---|
| Other Names | N-alpha-acetyltransferase 40, 2.3.1.-, N-acetyltransferase 11, NatD catalytic subunit, NAA40, NAT11 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 199-222 of HUMAN NAA40 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NAA40 {ECO:0000303|PubMed:19660095, ECO:0000312|HGNC:HGNC:25845} |
|---|---|
| Function | N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (PubMed:21935442, PubMed:25619998). In contrast to other N-alpha- acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (PubMed:21935442, PubMed:25619998). Acts as a negative regulator of apoptosis (PubMed:26666750). May play a role in hepatic lipid metabolism (By similarity). |
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Responsible for the acetylation of the N-terminal residues of histones H4 and H2A.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Taylor T.D.,et al.Nature 440:497-500(2006).
Polevoda B.,et al.BMC Proc. 3:S2-S2(2009).
Hole K.,et al.PLoS ONE 6:E24713-E24713(2011).
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