|Other Names||ADP-ribosylation factor-like protein 5A, ARL5A, ARFLP5, ARL5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2308a was selected from the N-term region of human ARL5 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Lacks ADP-ribosylation enhancing activity.|
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Provided below are standard protocols that you may find useful for product applications.
ARL5 belongs to the ARF family of GTP-binding proteins. With its distinctive nuclear/nucleolar localization and interaction with HP1alpha, the protein is developmentally regulated and may play a role(s) in nuclear dynamics and/or signaling cascades during embryonic development. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Lin, C.Y., et al., J. Cell. Sci. 115 (Pt 23), 4433-4445 (2002).He, H., et al., Gene Expr. 10 (5-6), 231-242 (2002).
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