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GGA2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UJY4
Other Accession GGA2_HUMAN
Clone Names 3102725
Peptide ID 3102725
Additional Information
Gene ID 23062
Other Names ADP-ribosylation factor-binding protein GGA2, Gamma-adaptin-related protein 2, Golgi-localized, gamma ear-containing, ARF-binding protein 2, VHS domain and ear domain of gamma-adaptin, Vear, GGA2, KIAA1080
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2317a was selected from the N-term region of human GGA2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GGA2
Synonyms KIAA1080
Function Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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GGA2 is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins.


Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Kalthoff, C., et al., Mol. Biol. Cell 13(11):4060-4073 (2002).Nielsen, M.S., et al., EMBO J. 20(9):2180-2190 (2001).Boman, A.L., et al., Mol. Biol. Cell 11(4):1241-1255 (2000).Hirst, J., et al., J. Cell Biol. 149(1):67-80 (2000).

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$ 80.00
Cat# BP2317a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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