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AGL Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P35573
Clone Names 3111006
Peptide ID 3111006
Additional Information
Gene ID 178
Other Names Glycogen debranching enzyme, Glycogen debrancher, 4-alpha-glucanotransferase, Oligo-1, 4-1, 4-glucantransferase, Amylo-alpha-1, 6-glucosidase, Amylo-1, 6-glucosidase, Dextrin 6-alpha-D-glucosidase, AGL, GDE
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2402a was selected from the Center region of human AGL . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGL
Synonyms GDE
Function Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in glycogen degradation.
Cellular Location Cytoplasm. Note=Under glycogenolytic conditions localizes to the nucleus
Tissue Location Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle
Research Areas
Citations (0)

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AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinicalvariability occurs which may be due to tissue-specific alternative splicing.


Horinishi, A., et al., J. Hum. Genet. 47(2):55-59 (2002).Bao, Y., et al., Genomics 38(2):155-165 (1996).Yang, B.Z., et al., J. Biol. Chem. 267(13):9294-9299 (1992).Yang-Feng, T.L., et al., Genomics 13(4):931-934 (1992).Bao, Y., et al., Gene 197 (1-2), 389-398 (1997).

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$ 80.00
Cat# BP2402a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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