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ZMPSTE24 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O75844
Other Accession NP_005848
Clone Names 3092507
Peptide ID 3092507
Additional Information
Gene ID 10269
Other Names CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2415a was selected from the Center region of human ZMPSTE24 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FACE1, STE24
Function Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein
Tissue Location Widely expressed. High levels in kidney, prostate, testis and ovary
Research Areas
Citations (0)

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ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.


Freije, J.M., et al., Genomics 58(3):270-280 (1999).Kumagai, H., et al., Biochim. Biophys. Acta 1426(3):468-474 (1999).Tam, A., et al., J. Cell Biol. 142(3):635-649 (1998).

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$ 80.00
Cat# BP2415a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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