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NYREN18 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9Y5A7
Clone Names 2120203
Peptide ID 2120203
Additional Information
Gene ID 51667
Other Names NEDD8 ultimate buster 1, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18, NUB1, NYREN18
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2510b was selected from the C-term region of human NYREN18 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NUB1
Synonyms NYREN18
Function Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
Cellular Location Nucleus. Note=Predominantly nuclear
Tissue Location Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2
Research Areas
Citations (0)

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NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.


Tanaka, T., et al., J. Biol. Chem. 278(35):32905-32913 (2003).Akey, D.T., et al., Hum. Mol. Genet. 11(22):2723-2733 (2002).Kito, K., et al., J. Biol. Chem. 276(23):20603-20609 (2001).Scanlan, M.J., et al., Int. J. Cancer 83(4):456-464 (1999).

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$ 80.00
Cat# BP2510b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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