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MARCKS Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P29966
Other Accession NP_002347
Clone Names 3083105
Peptide ID 3083105
Additional Information
Gene ID 4082
Other Names Myristoylated alanine-rich C-kinase substrate, MARCKS, Protein kinase C substrate, 80 kDa protein, light chain, 80K-L protein, PKCSL, MARCKS, MACS, PRKCSL
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2521a was selected from the N-term region of human MARCKS . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.
Cellular Location Cytoplasm, cytoskeleton. Membrane; Lipid-anchor
Research Areas
Citations (0)

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MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.


Rauch, M.E., et al., J. Biol. Chem. 277(16):14068-14076 (2002).Aderem, A., Biochem. Soc. Trans. 23(3):587-591 (1995).Rao, P.H., et al., Cytogenet. Cell Genet. 66(4):272-273 (1994).Taniguchi, H., et al., J. Biol. Chem. 268(14):9960-9963 (1993).Blackshear, P.J., J. Biol. Chem. 268(3):1501-1504 (1993).

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$ 80.00
Cat# BP2521a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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