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CPT1A Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P50416
Other Accession NP_001867
Clone Names 3083111
Additional Information
Gene ID 1374
Other Names Carnitine O-palmitoyltransferase 1, liver isoform, CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform, CPT I, CPTI-L, Carnitine palmitoyltransferase 1A, CPT1A, CPT1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2524a was selected from the N-term region of human CPT1A . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPT1A
Synonyms CPT1
Function Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.
Cellular Location Mitochondrion outer membrane; Multi- pass membrane protein
Tissue Location Strong expression in kidney and heart, and lower in liver and skeletal muscle
Research Areas
Citations (0)

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The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.


Rasmussen, B.B., et al., J. Clin. Invest. 110(11):1687-1693 (2002).Ogawa, E., et al., J. Hum. Genet. 47(7):342-347 (2002).Cook, G.A., et al., Am. J. Med. Sci. 318(1):43-48 (1999).IJlst, L., et al., J. Clin. Invest. 102(3):527-531 (1998).Britton, C.H., et al., Genomics 40(1):209-211 (1997).

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$ 80.00
Cat# BP2524a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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