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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PAPSS1 Antibody (Center) Blocking Peptide   

PAPSS1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43252
Other Accession NP_005434
Clone Names 3120505
Additional Information
Gene ID 9061
Other Names Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, PAPS synthase 1, PAPSS 1, Sulfurylase kinase 1, SK 1, SK1, Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT, Adenylyl-sulfate kinase, 3'-phosphoadenosine-5'-phosphosulfate synthase, APS kinase, Adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenylylsulfate 3'-phosphotransferase, PAPSS1, ATPSK1, PAPSS
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2607c was selected from the Center region of human PAPSS1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ATPSK1, PAPSS
Function Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
Tissue Location Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver Also expressed in high endothelial venules (HEV) cells and in cartilage
Research Areas
Citations (0)

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Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes. SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.


Venkatachalam, K.V., IUBMB Life 55(1):1-11 (2003).Xu, Z.H., et al., Biochem. Biophys. Res. Commun. 268(2):437-444 (2000).Venkatachalam, K.V., et al., J. Biol. Chem. 273(30):19311-19320 (1998).ul Haque, M.F., et al., Nat. Genet. 20(2):157-162 (1998).Girard, J.P., et al., FASEB J. 12(7):603-612 (1998).

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$ 80.00
Cat# BP2607c
(40 western blots)
Availability: In Stock
Bulk Size
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