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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CCND1 Antibody (N-term) Blocking Peptide   

CCND1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6FI00
Clone Names 80102161
Peptide ID 80102161
Additional Information
Gene ID 595
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2612a was selected from the N-term region of human CCND1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCND1 {ECO:0000313|EMBL:CAG38775.1}
Research Areas
Citations (0)

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CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of the gene encoding this protein, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.


He,Y.Y., Cancer Res. 68 (10), 3752-3758 (2008)Marsit,C.J., Clin. Cancer Res. 14 (8), 2371-2377 (2008)Caldon,C.E., Cancer Res. 68 (8), 3026-3036 (2008)

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$ 80.00
Cat# BP2612a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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