|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2704b was selected from the C-term region of human Ihh. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Intercellular signal essential for a variety of patterning events during development.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ihh (Indian hedgehog) is a critical and possibly direct regulator of joint development. In its absence, distribution and function of Gdf5-expressing interzone-associated cells are abnormal.
Kobayashi,T., Proc. Natl. Acad. Sci. U.S.A. 105 (6), 1949-1954 (2008)Gat-Yablonski,G.,J. Pediatr. Endocrinol. Metab. 20 (11), 1215-1222 (2007)Koyama,E., Ann. N. Y. Acad. Sci. 1116, 100-112 (2007)
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