|Other Names||Zinc finger protein ZIC 4, Zinc finger protein of the cerebellum 4, ZIC4|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2722b was selected from the C-term region of human ZIC4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to DNA.|
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Provided below are standard protocols that you may find useful for product applications.
ZIC4 is a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5.
Ishiguro,A., Biochem. Biophys. Res. Commun. 324 (1), 302-307 (2004)Grinberg,I., Nat. Genet. 36 (10), 1053-1055 (2004)Aruga,J., Gene 172 (2), 291-294 (1996)
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