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WIF1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y5W5 |
|---|---|
| Clone Names | 6072331 |
| Gene ID | 11197 |
|---|---|
| Other Names | Wnt inhibitory factor 1, WIF-1, WIF1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP2723a was selected from the N-term region of human WIF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | WIF1 |
|---|---|
| Function | Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 is a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.
References
Elston,M.S., Endocrinology 149 (3), 1235-1242 (2008)Clement,G., Cancer Sci. 99 (1), 46-53 (2008)Chan,S.L., Lab. Invest. 87 (7), 644-650 (2007)
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