|Other Names||Fructose-bisphosphate aldolase C, Brain-type aldolase, ALDOC, ALDC|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2736b was selected from the C-term region of human ALDOC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
ALDOC is a member of the fructose-biphosphate aldolase protein family. Expressed specifically in the hippocampus and Purkinje cells of the brain, this protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.
Buono,P.,FEBS Lett. 578 (3), 337-344 (2004)Buono,P.,Nucleic Acids Res. 16 (10), 4733 (1988)Rottmann,W.H.,Proc. Natl. Acad. Sci. U.S.A. 56 (4), 1275-1282 (1966)
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