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CYP26A1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43174
Other Accession Q5VXI0
Clone Names 80109113
Peptide ID 80109113
Additional Information
Gene ID 1592
Other Names Cytochrome P450 26A1, 114--, Cytochrome P450 retinoic acid-inactivating 1, Cytochrome P450RAI, hP450RAI, Retinoic acid 4-hydroxylase, Retinoic acid-metabolizing cytochrome, CYP26A1, CYP26, P450RAI1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2754c was selected from the Center region of human CYP26A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP26A1
Synonyms CYP26, P450RAI1
Function Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Tissue Location Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain
Research Areas
Citations (0)

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CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues.


Quere,R., Blood 109 (10), 4450-4460 (2007)Lee,S.J., Pharmacogenet. Genomics 17 (3), 169-180 (2007)Heise,R., J. Invest. Dermatol. 126 (11), 2473-2480 (2006)

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$ 80.00
Cat# BP2754c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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