|Other Names||Synaptophysin, Major synaptic vesicle protein p38, SYP|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2757a was selected from the Y81 region of human SYP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype|
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Provided below are standard protocols that you may find useful for product applications.
Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM].
Glantz,L.A., Neuroscience 149 (3), 582-591 (2007)Gonzalez-Aragoneses,F., Cancer 110 (8), 1776-1781 (2007)Bonanomi,D., Biochem. J. 404 (3), 525-534 (2007)
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