SOX1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O00570 |
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Clone Names | 71130124 |
Gene ID | 6656 |
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Other Names | Transcription factor SOX-1, SOX1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP2758c was selected from the Center region of human SOX1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SOX1 |
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Function | Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
Cellular Location | Nucleus. |
Tissue Location | Mainly expressed in the developing central nervous system |
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Provided below are standard protocols that you may find useful for product applications.
Background
SOX1 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq]
References
Malas,S., Mamm. Genome 8 (11), 866-868 (1997)
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