|Other Names||LIM/homeobox protein Lhx2, Homeobox protein LH-2, LIM homeobox protein 2, LHX2, LH2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2769a was selected from the Y213 region of human LHX2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
LHX2 belongs to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. This protein may function as a transcriptional regulator. This protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.
Glenn,D.J., J. Biol. Chem. 274 (51), 36159-36167 (1999)Wu,H.K., Oncogene 12 (6), 1205-1212 (1996)
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