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LHX2 Antibody (Y213) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P50458
Clone Names 80125120
Additional Information
Gene ID 9355
Other Names LIM/homeobox protein Lhx2, Homeobox protein LH-2, LIM homeobox protein 2, LHX2, LH2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2769a was selected from the Y213 region of human LHX2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LHX2
Synonyms LH2
Function Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

LHX2 belongs to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. This protein may function as a transcriptional regulator. This protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.

References

Glenn,D.J., J. Biol. Chem. 274 (51), 36159-36167 (1999)Wu,H.K., Oncogene 12 (6), 1205-1212 (1996)

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$ 277.78
Cat# BP2769a
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