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HNF4A Antibody (Center) Blocking Peptide

Synthetic peptide

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BP2778c 0.1 mg In Stock Call INQUIRE
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HNF4A Antibody (Center) Blocking Peptide - Product Information

Primary AccessionP41235
Clone Names80311227

HNF4A Antibody (Center) Blocking Peptide - Additional Information

Gene ID 3172
Target/Specificity
The synthetic peptide sequence used to generate the antibody AP2778c was selected from the Center region of human HNF4A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

HNF4A Antibody (Center) Blocking Peptide - Protein Information

Name HNF4A
Synonyms HNF4, NR2A1, TCF14
Function
Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine.
Cellular Location
Nucleus.

HNF4A Antibody (Center) Blocking Peptide - Related Products

AP2778a: HNF4A Antibody (S142)

AP2778c: HNF4A Antibody (Center)

AP9435a: HNF4A Antibody (N-term)

BP2778a: HNF4A Antibody (S142) Blocking Peptide

BP9435a: HNF4A Antibody (N-term) Blocking Peptide

AT2393a: HNF4A Antibody (monoclonal) (M04)

AT2394a: HNF4A Antibody (monoclonal) (M05)

AT2395a: HNF4A Antibody (monoclonal) (M07)

AJ1366a: HNF4 Alpha Antibody

AJ1366b: HNF4 Alpha Antibody

AP50429: Phospho-HNF4 alpha (Ser313) Antibody

HNF4A Antibody (Center) Blocking Peptide - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in HNF4A gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.

REFERENCES

Kritis A.A., Argyrokastritis A.Gene 173:275-280(1996) Yamagata K., Furuta H., Oda N.Nature 384:458-460(1996)Furuta H., Iwasaki N., Oda N.Diabetes 46:1652-1657(1997) Moeller A.M., Urhammer S.A.Diabetologia 40:980-983(1997)