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HNF4A Antibody (Center) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| BP2778c | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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HNF4A Antibody (Center) Blocking Peptide - Product info | |
| Primary Accession | P41235 |
| Clone Names | 80311227 |
| Calculated MW | 52785 Da |
HNF4A Antibody (Center) Blocking Peptide - Additional info | |
| Gene ID 3172 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP2778c was selected from the Center region of human HNF4A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
HNF4A Antibody (Center) Blocking Peptide - Protein Information | |
| Name HNF4A | |
| Synonyms HNF4, NR2A1, TCF14 | |
| Function Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine | |
| Cellular Location Nucleus. | |
HNF4A Antibody (Center) Blocking Peptide - Related products
AP2778a: HNF4A Antibody (S142)
AP2778c: HNF4A Antibody (Center)
AP3590a: Phospho-HNF4A-pS142 Antibody
AP9435a: HNF4A Antibody (N-term)
RI12524: HNF4A predesign siRNA
BP2778a: HNF4A Antibody (S142) Blocking Peptide
BP2778c: HNF4A Antibody (Center) Blocking Peptide
BP3590a: Phospho-HNF4A-pS142 Antibody Blocking Peptide
BP9435a: HNF4A Antibody (N-term) Blocking Peptide
AT2393a: HNF4A Antibody (monoclonal) (M04)
AT2394a: HNF4A Antibody (monoclonal) (M05)
AT2395a: HNF4A Antibody (monoclonal) (M07)
AJ1040a: AMPK-alpha1 Antibody Phospho-pS487
HNF4A Antibody (Center) Blocking Peptide - Research Areas
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BACKGROUND
HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in HNF4A gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
REFERENCES
Kritis A.A., Argyrokastritis A.Gene 173:275-280(1996) Yamagata K., Furuta H., Oda N.Nature 384:458-460(1996)Furuta H., Iwasaki N., Oda N.Diabetes 46:1652-1657(1997) Moeller A.M., Urhammer S.A.Diabetologia 40:980-983(1997)