HNF4A Antibody (Center) Blocking Peptide
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|BP2778c||0.1 mg||In Stock||Call||INQUIRE|
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HNF4A Antibody (Center) Blocking Peptide - Product Information
HNF4A Antibody (Center) Blocking Peptide - Additional Information
|Gene ID 3172|
Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4, HNF4A, HNF4, NR2A1, TCF14
The synthetic peptide sequence used to generate the antibody AP2778c was selected from the Center region of human HNF4A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
HNF4A Antibody (Center) Blocking Peptide - Protein Information
|Synonyms HNF4, NR2A1, TCF14|
Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine.
HNF4A Antibody (Center) Blocking Peptide - Related Products
HNF4A Antibody (Center) Blocking Peptide - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in HNF4A gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
Kritis A.A., Argyrokastritis A.Gene 173:275-280(1996) Yamagata K., Furuta H., Oda N.Nature 384:458-460(1996)Furuta H., Iwasaki N., Oda N.Diabetes 46:1652-1657(1997) Moeller A.M., Urhammer S.A.Diabetologia 40:980-983(1997)