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RCHY1 Antibody (N-term H44) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96PM5
Clone Names 80612019
Peptide ID 80612019
Additional Information
Gene ID 25898
Other Names RING finger and CHY zinc finger domain-containing protein 1, 632-, Androgen receptor N-terminal-interacting protein, CH-rich-interacting match with PLAG1, E3 ubiquitin-protein ligase Pirh2, RING finger protein 199, Zinc finger protein 363, p53-induced RING-H2 protein, hPirh2, RCHY1, ARNIP, CHIMP, PIRH2, RNF199, ZNF363
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2796a was selected from the N-term region of human RCHY1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RCHY1
Synonyms ARNIP, CHIMP, PIRH2, RNF199, ZNF363
Function Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
Cellular Location Nucleus. Nucleus speckle. Cytoplasm.
Research Areas
Citations (0)

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RCHY1 protein has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. Gene of RCHY1 is oncogenic because loss of p53 function contributes directly to malignant tumor development.


Sheng,Y., Nat. Struct. Mol. Biol. 15 (12), 1334-1342 (2008)Maruyama,S., Mol. Cell. Biochem. 307 (1-2), 73-82 (2008)Duan,S., EMBO J. 26 (13), 3062-3074 (2007)Duan,W., J. Natl. Cancer Inst. 96 (22), 1718-1721 (2004)

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$ 80.00
Cat# BP2796a
Availability: In Stock
Bulk Size
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