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WDYHV1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96HA8
Clone Names 80317132
Peptide ID 80317132
Additional Information
Gene ID 55093
Other Names Protein N-terminal glutamine amidohydrolase, 351-, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase, WDYHV motif-containing protein 1, WDYHV1, C8orf32, NTAQ1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2809c was selected from the Center region of human WDYHV1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C8orf32, NTAQ1
Function Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N- terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C- terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine (By similarity).
Cellular Location Cytoplasm, cytosol. Nucleus
Research Areas
Citations (0)

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Lim,J., Cell 125 (4), 801-814 (2006)

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$ 80.00
Cat# BP2809c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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