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DLG7 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15398
Peptide ID 26343
Additional Information
Gene ID 9787
Other Names Disks large-associated protein 5, DAP-5, Discs large homolog 7, Disks large-associated protein DLG7, Hepatoma up-regulated protein, HURP, DLGAP5, DLG7, KIAA0008
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DLGAP5
Synonyms DLG7, KIAA0008
Function Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Cellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells
Tissue Location Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta
Research Areas
Citations (0)

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Background

DLG7 is potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. DLG7 is mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. DLG7 is key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.

References

de Reynies, A., et al. J. Clin. Oncol. 27(7):1108-1115(2009)Wong, J., et al. Mol. Biol. Cell 19(5):2083-2091(2008)Gudmundsson, K.O., et al. Stem Cells 25(6):1498-1506(2007)

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$ 80.00
Cat# BP2810c
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