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KRT19 Antibody (Center) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP2823c | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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KRT19 Antibody (Center) Blocking Peptide - Product info | |
| Primary Accession | P08727 |
| Clone Names | 80808051 |
| Calculated MW | 44106 Da |
KRT19 Antibody (Center) Blocking Peptide - Additional info | |
| Gene ID 3880 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP2823c was selected from the Center region of human KRT19. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
KRT19 Antibody (Center) Blocking Peptide - Protein Information | |
| Name KRT19 | |
| Function Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle | |
| Tissue Location Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin | |
KRT19 Antibody (Center) Blocking Peptide - Related products
AP2823b: KRT19 Antibody (C-term)
AP2823c: KRT19 Antibody (Center)
AP3631a: Phospho-KRT19-pS46 Antibody
RI12958: KRT19 predesign siRNA
LY10852a: KRT19 Over-expression Lysate
BP2823a: KRT19 Antibody (S46) Blocking Peptide
BP2823b: KRT19 Antibody (C-term) Blocking Peptide
BP2823c: KRT19 Antibody (Center) Blocking Peptide
BP3631a: Phospho-KRT19-pS46 Antibody Blocking Peptide
AO1226a: Cytokeratin 19 Antibody
AO1239a: Cytokeratin 19 Antibody
AJ1224a: Cytokeratin-19 Antibody
KRT19 Antibody (Center) Blocking Peptide - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.
REFERENCES
Bonzanini,M., Acta Cytol. 52 (5), 541-548 (2008)Yang,X.R., Clin. Cancer Res. 14 (12), 3850-3859 (2008)Maurer,J., PLoS ONE 3 (10), E3451 (2008)