|Other Names||1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-3, Phosphoinositide phospholipase C-beta-3, Phospholipase C-beta-3, PLC-beta-3, PLCB3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2826c was selected from the Center region of human PLCB3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.|
|Cellular Location||Membrane; Peripheral membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Maeng,Y.S., Blood 113 (1), 233-243 (2009)Brugnoli,F., Cell. Signal. 19 (8), 1701-1712 (2007)Bertagnolo,V., Carcinogenesis 28 (8), 1638-1645 (2007)
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