|Other Names||Prefoldin subunit 6, Protein Ke2, PFDN6, HKE2, PFD6|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2836a was selected from the N-term region of human PFDN6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|
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Provided below are standard protocols that you may find useful for product applications.
PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Ostrov,D.A., Tissue Antigens 69 (2), 181-188 (2007)Simons,C.T., J. Biol. Chem. 279 (6), 4196-4203 (2004)Vainberg,I.E., Cell 93 (5), 863-873 (1998)
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