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DCC1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9BVC3
Other Accession NP_076999.2
Clone Names 80317158
Peptide ID 80317158
Additional Information
Gene ID 79075
Other Names Sister chromatid cohesion protein DCC1, Defective in sister chromatid cohesion protein 1 homolog, DSCC1, DCC1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DSCC1
Synonyms DCC1
Function Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
Cellular Location Nucleus.
Research Areas
Citations (0)

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CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 arecomponents of an alternative replication factor C (RFC) (see MIM600404) complex that loads PCNA (MIM 176740) onto DNA during Sphase of the cell cycle (Merkle et al., 2003 [PubMed 12766176];Bermudez et al., 2003 [PubMed 12930902]).


Murakami, T., et al. J. Biol. Chem. 285(45):34608-34615(2010)Terret, M.E., et al. Nature 462(7270):231-234(2009)Watrin, E., et al. Curr. Biol. 16(9):863-874(2006)Bermudez, V.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(18):10237-10242(2003)Merkle, C.J., et al. J. Biol. Chem. 278(32):30051-30056(2003)

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$ 80.00
Cat# BP2874b
Availability: In Stock
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