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CD49e Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P08648
Clone Names 81020027
Peptide ID 81020027
Additional Information
Gene ID 3678
Other Names Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e, Integrin alpha-5 heavy chain, Integrin alpha-5 light chain, ITGA5, FNRA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2876c was selected from the Center region of human CD49e. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ITGA5
Synonyms FNRA
Function Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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CD49e belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein is the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.


Boehmler,A.M., J. Immunol. 182 (11), 6789-6798 (2009)Okazaki,T., Am. J. Pathol. 174 (6), 2378-2387 (2009)Schornberg,K.L., Proc. Natl. Acad. Sci. U.S.A. 106 (19), 8003-8008 (2009)

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$ 80.00
Cat# BP2876c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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