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APRT Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07741
Clone Names 81202006
Peptide ID 81202006
Additional Information
Gene ID 353
Other Names Adenine phosphoribosyltransferase, APRT, APRT
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2893b was selected from the C-term region of human APRT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.


Silva,C.H., et. al.,J. Biomol. Struct. Dyn. 25 (6), 589-597 (2008)Di Pietro,V., et. al., Clin. Biochem. 40 (1-2), 73-80 (2007)

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$ 80.00
Cat# BP2893b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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