|Other Names||Phosphoglycerate mutase 1, BPG-dependent PGAM 1, Phosphoglycerate mutase isozyme B, PGAM-B, PGAM1, PGAMA|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2923c was selected from the Center region of human PGAM1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 220.127.116.11 (synthase) and EC 18.104.22.168 (phosphatase), but with a reduced activity.|
|Tissue Location||In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues|
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Provided below are standard protocols that you may find useful for product applications.
PGAM1 can be interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. It can also catalyze the reaction of EC 22.214.171.124 (synthase) and EC 126.96.36.199 (phosphatase), but with a reduced activity.
Martins-de-Souza,D., et.al., BMC Psychiatry 9, 17 (2009)Oh,S.J., et.al., Muscle Nerve 34 (5), 572-576 (2006)
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