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PGAM1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P18669 |
|---|---|
| Clone Names | 81205089 |
| Gene ID | 5223 |
|---|---|
| Other Names | Phosphoglycerate mutase 1, BPG-dependent PGAM 1, Phosphoglycerate mutase isozyme B, PGAM-B, PGAM1, PGAMA |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP2923c was selected from the Center region of human PGAM1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PGAM1 (HGNC:8888) |
|---|---|
| Synonyms | PGAMA |
| Function | Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglyceratea crucial step in glycolysis, by using 2,3- bisphosphoglycerate (PubMed:23653202). Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho- glyceroyl phosphate (PubMed:23653202). |
| Tissue Location | Expressed in the liver and brain. Not found in the muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PGAM1 can be interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. It can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
References
Martins-de-Souza,D., et.al., BMC Psychiatry 9, 17 (2009)Oh,S.J., et.al., Muscle Nerve 34 (5), 572-576 (2006)
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