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PRDX6 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P30041
Clone Names 81205104
Peptide ID 81205104
Additional Information
Gene ID 9588
Other Names Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 311-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2927b was selected from the C-term region of human PRDX6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDX6
Synonyms AOP2, KIAA0106
Function Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Cellular Location Cytoplasm. Lysosome. Cytoplasmic vesicle. Note=Also found in lung secretory organelles.
Research Areas
Citations (0)

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Background

PRDX6is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

References

Sorokina,E.M., et.al., Am. J. Physiol. Lung Cell Mol. Physiol. 297 (5), L871-L880 (2009)Manevich,Y., et.al., Arch. Biochem. Biophys. 485 (2), 139-149 (2009)

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$ 80.00
Cat# BP2927b
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