|Other Names||D-3-phosphoglycerate dehydrogenase, 3-PGDH, PHGDH, PGDH3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
3-Phosphoglycerate dehydrogenase (PHGDH; EC 220.127.116.11)catalyzes the transition of 3-phosphoglycerate into3-phosphohydroxypyruvate, which is the first and rate-limiting stepin the phosphorylated pathway of serine biosynthesis, usingNAD+/NADH as a cofactor.
Du, H., et al. Reproduction 139(1):237-245(2010)Burton, R.L., et al. Biochemistry 48(22):4808-4815(2009)Kim, J.W., et al. Psychiatr. Genet. 19 (3), 161 (2009) :Tabatabaie, L., et al. Hum. Mutat. 30(5):749-756(2009)
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