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CD138 Antibody (C-term K281) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P18827
Clone Names 81201124
Peptide ID 81201124
Additional Information
Gene ID 6382
Other Names Syndecan-1, SYND1, CD138, SDC1, SDC
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2948b was selected from the C-term region of human CD138. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDC1
Synonyms SDC
Function Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Cellular Location Membrane; Single-pass type I membrane protein. Secreted. Secreted, exosome. Note=Shedding of the ectodomain produces a soluble form.
Research Areas
Citations (0)

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Background

CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.

References

Rikova,K., et.al., Cell 131 (6), 1190-1203 (2007)Endo,K., et.al., J. Biol. Chem. 278 (42), 40764-40770 (2003)

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$ 80.00
Cat# BP2948b
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