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HNRPL Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P14866
Clone Names 81205058
Peptide ID 81205058
Additional Information
Gene ID 3191
Other Names Heterogeneous nuclear ribonucleoprotein L, hnRNP L, HNRNPL, HNRPL
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2950c was selected from the Center region of human HNRPL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HNRPL
Function Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.
Cellular Location Nucleus, nucleoplasm. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs
Research Areas
Citations (0)

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HNRPL is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. L is associated with most nascent transcripts including those of the landmark giant loops of amphibian lampbrush chromosomes.


Hahm,B.,, FEBS Lett. 425 (3), 401-406 (1998)Funke,B.,, Nucleic Acids Res. 24 (19), 3821-3828 (1996)

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$ 80.00
Cat# BP2950c
(40 western blots)
Availability: In Stock
Bulk Size
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