|Other Names||GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase, GMPS|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2953b was selected from the C-term region of human GMPS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.|
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Provided below are standard protocols that you may find useful for product applications.
GMPS is involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
Nakamura,J., et.al., J. Biol. Chem. 270 (40), 23450-23455 (1995)Nakamura,J. et.al., J. Biol. Chem. 270 (13), 7347-7353 (1995)
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