|Other Names||G2/mitotic-specific cyclin-B1, CCNB1, CCNB|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP3078a was selected from the 119-133 |
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Essential for the control of the cell cycle at the G2/M (mitosis) transition.|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
Yoshida, T., et al., Ann. Oncol. 15(2):252-256 (2004).Chang, D.C., et al., J. Biol. Chem. 278(39):37865-37873 (2003).Sanchez, V., et al., J. Virol. 77(24):13214-13224 (2003).Li, J.Q., et al., Int. J. Oncol. 22(5):1101-1110 (2003).Porter, L.A., et al., Blood 101(5):1928-1933 (2003).
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