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Phospho-TyK2-Y1054/1055 Antibody Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P29597
Clone Names 4022310
Additional Information
Gene ID 7297
Other Names Non-receptor tyrosine-protein kinase TYK2, TYK2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP3283a was selected from the region of human Phospho-TyK2-Y1054/1055. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TYK2
Function Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.
Tissue Location Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines
Research Areas
Citations (0)

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TYK2 is likely involved in intracellular signal transduction via involvement in the initiation of type I IFN signaling. TYK2 Phosphorylates the interferon-alpha/beta receptor alpha chain. In animal models TYK2 is an important regulator of lymphoid tumor surveillance.


Lukashova, V., et al., J. Immunol. 171(7):3794-3800 (2003).Kiian, I., et al., Thromb. Haemost. 89(5):904-914 (2003).Ragimbeau, J., et al., EMBO J. 22(3):537-547 (2003).Trask, B., et al., Genomics 15(1):133-145 (1993).Firmbach-Kraft, I., et al., Oncogene 5(9):1329-1336 (1990).

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$ 80.00
Cat# BP3283a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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