|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP3288a was selected from the region of human Phospho-NR4A1-S351. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.
Lu, L., et al., J. Clin. Endocrinol. Metab. 89(8):4113-4118 (2004).Castro-Obregon, S., et al., J. Biol. Chem. 279(17):17543-17553 (2004).Lin, B., et al., Cell 116(4):527-540 (2004).Choi, J.W., et al., Cancer Res. 64(1):35-39 (2004).Ye, X., et al., Int. J. Biochem. Cell Biol. 36(1):98-113 (2004).
If you have any additional inquiries please email technical services at firstname.lastname@example.org.